Qt Designer required for PyQt?

[Kevin Walzer]

  is it possible to write the GUI code for PyQt applications by hand or 
is using the Qt Designer an essential part of the process? Coming from a 
Tkinter background, with a little exposure to wxPython, I'm very 
comfortable and productive writing GUI code by hand. I understand the 
appeal of using the GUI builder to visualize how your GUI will look, but 
it also can add a layer of complexity. Does anyone write complex PyQt 
apps without using Designer?

-- 
Kevin Walzer
Code by Kevin
http://www.codebykevin.com