GUI - Windows: Where to get started

[Cappy2112]

if you want something one step simpler than wX & TK take a look at

http://www.averdevelopment.com/python/EasyDialogs.html

or

http://www.ferg.org/easygui/index.html

You loose a lot of flexibility, but get ultra simple (and
plain-looking)  widgets, without all of the complexity of of a gui
Framework, expecially wx.
This is a quick and dirty way to add some really simple dialogues to a
Python program.
But you don't get exposed to the concepts you need to know to work with
a full-powered framework.

Try PythonCard, for a framework that abstracts wx even further, but
still providing most of the functionality (if not all of it) of wx.

Alo take a look at QT/pyQT (another framework and it's wrapper)