Python as alternative to Visual Basic

[Neuruss]

I suggest PythonCard. 
It's by far the easiest tool for creating cross-platform GUI apps
based on wxPython in a visual way (dragging and dropping widgets into
a form). The downside is that some widgets are not yet implemented,
but you can use the most important ones.

Another good thing is that it creates authomatically two files: one
for the presentation (form, buttons, etc) and another for the code,
which makes it very simple and clean.