shutil.copyfile problem for GIS data

[supercooper]

import shutil
import os

src = "c:\mydata\test\mygeo.mdb"
dst = "v:\updated\data\mygeo.mdb"

shutil.copyfile(src,dst)

This should totally work, do it all the time, but no one can be
connected to the database, ie have ArcMap or ArcCatalog open at the
time of copy, or the .ldb lock will kill it. I do all of my copies in
the early AM.