Python error on Mac

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When trying to do some things on my Mac (starting Lyx, compiling Latex 
via TextMate) I get this error:

python: execv: 
/Library/Frameworks/Python.framework/Versions/2.5/Resources/Python.app/Contents/MacOS/Python: 
No such file or directory

I (and people on Lyx and TextMate lists) are at a complete loss as to 
why this is happening. I didn't (at least intentionally) fiddle with 
Python setup.

Thanks!