separation events

[Ghido]

Hi all, i'm writing a software with python and wxpython for manage the
quality/environmental/security system for the my factory. I want to
separate the gui structure from the events and database operations for
obtain a very modular software, for this reason i start to use
sqlalchemy. Unfortunately i don't understand if is possibile to have a
file with only the gui structure and another file with the database
operations and the events of the gui. It is possibile? the use of
sqlalchemy is a good thing?
Thanks a lot

Ghido