What is your favorite Python web framework?

[Jeff Shell]

Zope 3, far and away. There's great documentation, quite a few load
handling options (different types of caching and ZEO to distribute ZODB
caches to multiple machines). Zope 3 aggressively favors small
cooperating objects (Zope 2 was inheritance heavy, making
customization, extension, etc, a big chore). There are two books in
print already and it's quite mature already.

Don't discard Zope 3 becaue of what you've heard about Zope 2. Zope 3
is a very different animal.