Regular Expressions in Python

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Dear Gurus,

  I am trying to find out how to write an effective regular expression
in python for the following scenario:

   "any number of leading spaces at the beginning of a line" "follow
by a string" "there maybe a string that starts with *"

for example:

  END  *This is a comment

but I don't want to match this:

   END  e * This is a line with an error (e)

thanks,
Noel