what is best for web development??

[ketulp_baroda]

i am developing an issue tracking system 
the primary requirements are
1)it should be platform independent which i think python will take 
care of
2)it should have customizeable gui .I am thinking of using templates 
for this like Cheetah. Is there any other better solution to Cheetah?
The problem i am facing here is i dont know what to use for 
development of the application. I came across many ways to develop 
web application in python which I already specified like 
i)the cgi module in python
ii)Python Server Pages
iii)Quixote
iv)WebWare
v)Zope etc.
I want to choose such an environment so that i dont have to install 
other softwares to run my application.For eg. I think if I develop 
using zope then the client also has to install zope to run my 
software and i dont want this.