Civilization IV uses Python for scripting

[Terry Reedy]

According to PCGamer, Jan05, p52:

"*Civilization IV* [Sid Meier's latest, due out next year] has been 
designed to fully support the mod community.  The game is written using 
flexible XML data files and the Python scripting language so modders will 
have no trouble at all creating their own personalized worlds, units, 
techniques, and historical events.  Advanced modders will even be able to 
control the AI."

Other commercial games have use Python as an undocumented private scripting 
language, but this is the first I know of that will also make it the user 
scripting language -- presumably with documentation of the user-usable 
functions, classes, and methods.

Terry J. Reedy