How easy is it to create graphical user interface with Python?

[Johan Trygg]

Hi,
I am a complete beginner to Python, but I have heard many good things
about it. I am thinking about creating a GUI software that will
contain some linear algebra, 2D plots (scatter, histogram, line plots)
and a nice GUI with menus.
I am currently using Matlab to do this but does anyone have experience
with Python to create such a software.

Hope to hear from you soon,