How many is "too many" with lists?

[Matthew Hirsch]

Hi all,

Is there a rough number of elements in a list that python or a computer 
has trouble dealing with?  I'm using a P233 with 64MB RAM.  I have 
~25000 elements in a list, and things seem to be slowing down.  Is there 
some number that I should try avoiding?

Thanks,
Matt